Cell type-specific deconvolution of heterogeneous tumor samples with two or three components using expression data from RNAseq or microarray platforms


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Documentation for package ‘DeMixT’ version 1.6.0

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DeMixT Deconvolution of heterogeneous tumor samples with two or three components using expression data from RNAseq or microarray platforms
DeMixT_DE Estimates the proportions of mixed samples for each mixing component
DeMixT_GS Estimates the proportions of mixed samples for each mixing component using profile likelihood gene selection
DeMixT_S2 Deconvolves expressions of each individual sample for unknown component
Optimum_KernelC Kernel function for optimizing parameters and hidden variables in DeMixT
simulate_2comp Function to simulate two-component test data
simulate_3comp Function to simulate three-component mixed cell line test data
test.data.2comp Simulated two-component test data
test.data.3comp Simulated three-component mixed cell line test data